Dr Molecular Biology
PB (MSc Biology, PhD Medical Sciences) is a Dutch molecular biologist, science writer & author. He worked for several research institutes, incl. the University of Groningen (Netherlands), the University of Sydney (Australia), the University of Basel (Switzerland) and the university of Zurich (Switzerland). An expert on molecular and genome biology of gene expression and signal transduction networks, PB published over 70 articles in leading international journals, including the New Eng. J. Med. Currently, PB works on the non-protein coding part of the genome and how it is involved in generating variation through gene regulatory reprogramming. He is assessing the hypothesis that transposable elements are the precursors of a retroviruses. He is the author of the international best seller “Darwin Revisited or how to understand biology in the 21st century” and a board member of the ICLSS, an international consortium of life science scientists that critically follows the science behind the corona-measures.
If you really need a vaccine, it is important to know how they work and what the potential adverse effects might be. PB briefly discusses the mechanisms of action of DNA-, RNA- and protein-based vaccines, which are currently administered to major part of the human population. He also focusses on possible side effects, which may relate to less well-studied molecular mechanisms. Given that DNA-vaccines are able to integrate in the DNA, it cannot be excluded that DNA vaccines cause long-term side effects when they accidentally disrupt genes and/and gene regulatory networks. Although this is known since several decades, literature on how often this may occur for Covid vaccines is absent. The same holds for RNA vaccines. Although all cells have the potential to express reverse transcriptase and endonuclease from socalled endogenous retroviruses, there is no literature addressing the question whether or not RNA vaccines can be reverse transcribed and integrated in our own DNA. The well-studied protein-based vaccines cannot integrate in the DNA and long-term side effects based on mutagenic properties can therefore be excluded.